{"id":11982,"date":"2018-07-04T07:36:39","date_gmt":"2018-07-04T07:36:39","guid":{"rendered":"https:\/\/businessbooster.ro\/?p=11982"},"modified":"2025-03-05T12:08:39","modified_gmt":"2025-03-05T10:08:39","slug":"bioprinting-2018s-main-breakthroughs-so-far","status":"publish","type":"post","link":"https:\/\/ambogdan.com\/bioprinting-2018s-main-breakthroughs-so-far\/","title":{"rendered":"3D Bioprinting – 2018\u2019s Main Breakthroughs So Far"},"content":{"rendered":"
3D Bioprinting tissue isn\u2019t a new idea, yet the method, so far, has been limited to tissues that are very small or very thin and lack blood vessels. Signs of Progress<\/span>\u00a0have been made across the globe.\u00a0We have already seen lab-grown ears, bladders, blood vessels, and other parts implanted in patients and the\u00a0<\/span>world’s first bioprinted tibia transplant<\/a>. We’ve also seen how a\u00a03D printed prosthetic hands<\/a> changed a few kids’ lives. And, yes, the medical world has not reached that point where it can 3D bioprint a fully functional human heart, yet scientists do believe that day is only a few years away. Here are some of the most relevant 3D bioprinting breakthroughs registered in 2018’s first six months that are worth looking at, if you share my interest in emerging technologies able to change the face of modern medicine. \u00a0<\/span><\/p>\r\n The underlying structure and actual printout of the scaffold – (a) Cylindrical pore microstructure, adapted from47 and (b) 8 unit cells printed; thawed printed 8 cell structure in (c) isometric view and (d) side view. Scale bars, (c) 10\u2009mm and (d) 5\u2009mm. Source: nature.com<\/em><\/p><\/div>\r\n Back in January 2018, <\/span>Imperial College London researchers announced that their new <\/span>3D printing technique allows researchers to replicate biological structures, which could be used for tissue regeneration and replica organs. To do so, they use <\/span>using cryogenics (freezing) and 3D printing techniques. <\/span><\/p>\r\n According to <\/span>Zhengchu Tan<\/a>, one of the researchers from the Department of Mechanical Engineering at Imperial, <\/span>“At the moment we have created structures a few centimetres in size, but ideally, we’d like to create a replica of a whole organ using this technique.”<\/em><\/p>\r\n But, there are two things this new approach can bring to the medical world and benefit patients in need of complex surgeries and organ transplants: <\/span><\/p>\r\n <\/p>\r\n Just one month later, <\/span>University of Twente, <\/span>Netherlands<\/span>, \u00a0scientists <\/span>announced that they were successful <\/span>in printing 3D structures with living cells. This special technique enables the fast and \u2018in-flight\u2019 production of micro building blocks that are viable and can be used for repairing damaged tissue, for example. As opposed to other 3D printing techniques using heat or UV light both potentially damaging living cells, this microfluidic approach is extremely promising as the damaged tissue is repaired by using cultured cell material of the patient.<\/span><\/p>\r\n BIOLIFE4D, a Chicago-based medical tech firm specializing in 3D bioprinting and tissue engineering, announced it has successfully demonstrated its ability to 3D bioprint human cardiac tissue, namely a human cardiac patch. <\/span>The whole process was completed in just a few days and much sooner than anticipated. <\/span> What makes BIOLIFE4D\u2019s bioprinting process<\/a> so special is the fact that it provides the ability to reprogram a patient\u2019s own (white) blood cells to iPS cells. Also, it differentiates the iPS cells into different types of cardiac cells needed to 3D bioprint not only a cardiac patch but a human heart viable for transplant. <\/span>For BIOLIFE4D the next steps will be on will be constructing valves, blood vessels and a mini-heart as it seeks to progress to 3D bioprinting a full human heart.<\/span><\/p>\r\n In May 2018, s<\/span>cientists at Newcastle University, UK, <\/span>have <\/span>3D-printed the first human corneas. This is quite an amazing piece of news for all those people already suffering or being threatened by blindness. Their research claims that it took only 10 minutes to obtain the 3D-printed cornea that matched the patient’s unique specifications (size and shape). However, this is just the beginning and it will take several years the improve the technique, so it can be used on real patient transplants in hospitals.<\/span><\/p>\r\nSuper soft structures that replicate the brain and lungs<\/h2>\r\n
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3D printing of living cells<\/h2>\r\n
Successfully 3D bioprints of human heart tissues<\/h2>\r\n
World’s first 3D-printed cornea<\/h2>\r\n